BIO 148

Directions:
​
1.​Print off the questions below for Cracking the Code of Life
2.​Click on the URL for NOVA listed below (or cut and paste into the address line)
​http://www.pbs.org/wgbh/nova/genome/program_adv.html

​3.​Scroll down to Watch Video Online
​4.​Choose program 1: Instructions for a Human Being
​
​5.​Select the speed in Quick time that you wish to watch it.
If the full screen version does not play smoothly, you may have an older model of computer that needs the next selection : (448 X 336.43 MB)
​6.​There are several presentation to Cracking the Code of Life.
​Watch 1 through 6.
​7.​Answer the questions below: ( the questions are in sequence)
​8.​Complete the “Wrap up study” questions.
​9.​When you have completed this assignment, submit your answers to your instructor via email (F07 SE2 your name as the subject line on the email).
​Do a good job. Remember this project is valued at 20 points.
​

Section 1: Instructions for a Human Being
1.​How would you describe the appearance of DNA taken from the test tube,?
2. How different are we from a banana?
3. How long is the human genome?
4.​What will being able to sequence the human genome tell us?

Section 2: Getting the Letters Out
1.​How did the announcer describe the DNA molecule?
2.​How genetically the same are any two babies?
3.​How many nucleotides make up the human genome?
4.​The date for launching the human genome project was ________ .​
5. ​How long did it take to find the gene sequence for cystic fibrosis ?
6. ​What percentage of the DNA nucleotides is active and important?
7. What helped speed up the sequencing project? How fast did it speed up the sequencing?
8. The DNA sequence was described by Eric Lander as being akin to a _________ __________.
9. Why is it important to know the human genome sequence (all parts, every letter)?

Section 3: One Wrong Letter
1. Example of a genetic disorder:
​The name of the disorder is _________________
​The cause of the disorder:
​What happens because of that change?
​What is the eventual outcome of the disorder?
​The disorder is inherited by
​What population of people carry this gene?
2. What can be done if you know all the base pairs making up the human?

Section 4: Sequencing Race Begins
1.​Government scientists through it would take how long to sequence the human genome?
2.​How is DNA code read?
3. ​Describe the person who set up a private enterprise to sequence the human genome.​
4.​Name the company that he started. What does the name mean?
5.​Briefly describe the process utilized.
6.​In 1998, how long did Venter think the project would take?

Section 5: Ramping Up
1. Name the two main labs and who was in charge of the projects.
2.​How many different labs were working on the project at that time? Name a few.
3. List a few of the problems they faced with the project.
4.​What date did the labs have 1/3 of the human genome sequenced?

Section 6: Genetic Variation
1. Whose genes were actually sequenced?
2. How different are any 2 humans?
3. Which kinds of animals are most different from each other – humans or chimpanzees?
4. Why are we as humans more closely related genetically than chimpanzees?
5. The human genome evolved from this continent __________ .
6​Explain why the difference between us and the banana genome are only 50% different.
7. ​Compare the human genome to the yeast genome.

Wrap-up study:
Easiest way to get to the website for this study: http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=gnd&ref=toc
At the new page titled Genes and Diseases, click on one of the 24 chromosomes shown at the top of the page
When the chromosome comes up, make note of the chromosome you choose.
​Note how many genes are located on the particular chromosome that you choose.
​Click on a disorder located on this chromosome and read about the particular disorder.
​Briefly give the characteristics of this genetic disorder.

If all else fails and the URL at the top of the Wrap-up study does not get you where you need to be, try the following:
1.​Select the web site http://www.ornl.gov/sci/techresources/Human_Genome/posters/chromosome/
2.​Click on Disorder Guide
3.​Scroll down to Gene and Diseases . Click on this hot link.
4.​On the page below the title Genes and Diseases click on the words “Click here”
5.​At the new page titled Genes and Diseases, click on one of the 24 chromosomes shown at the top of the page.
6. ​From here follow the directions for the activity listed in the Wrap-up study.
​

BIO 148

Directions:
​
1.​Print off the questions below for Cracking the Code of Life
2.​Click on the URL for NOVA listed below (or cut and paste into the address line)
​http://www.pbs.org/wgbh/nova/genome/program_adv.html

​3.​Scroll down to Watch Video Online
​4.​Choose program 1: Instructions for a Human Being
​
​5.​Select the speed in Quick time that you wish to watch it.
If the full screen version does not play smoothly, you may have an older model of computer that needs the next selection : (448 X 336.43 MB)
​6.​There are several presentation to Cracking the Code of Life.
​Watch 1 through 6.
​7.​Answer the questions below: ( the questions are in sequence)
​8.​Complete the “Wrap up study” questions.
​9.​When you have completed this assignment, submit your answers to your instructor via email (F07 SE2 your name as the subject line on the email).
​Do a good job. Remember this project is valued at 20 points.
​

Section 1: Instructions for a Human Being
1.​How would you describe the appearance of DNA taken from the test tube,?
2. How different are we from a banana?
3. How long is the human genome?
4.​What will being able to sequence the human genome tell us?

Section 2: Getting the Letters Out
1.​How did the announcer describe the DNA molecule?
2.​How genetically the same are any two babies?
3.​How many nucleotides make up the human genome?
4.​The date for launching the human genome project was ________ .​
5. ​How long did it take to find the gene sequence for cystic fibrosis ?
6. ​What percentage of the DNA nucleotides is active and important?
7. What helped speed up the sequencing project? How fast did it speed up the sequencing?
8. The DNA sequence was described by Eric Lander as being akin to a _________ __________.
9. Why is it important to know the human genome sequence (all parts, every letter)?

Section 3: One Wrong Letter
1. Example of a genetic disorder:
​The name of the disorder is _________________
​The cause of the disorder:
​What happens because of that change?
​What is the eventual outcome of the disorder?
​The disorder is inherited by
​What population of people carry this gene?
2. What can be done if you know all the base pairs making up the human?

Section 4: Sequencing Race Begins
1.​Government scientists through it would take how long to sequence the human genome?
2.​How is DNA code read?
3. ​Describe the person who set up a private enterprise to sequence the human genome.​
4.​Name the company that he started. What does the name mean?
5.​Briefly describe the process utilized.
6.​In 1998, how long did Venter think the project would take?

Section 5: Ramping Up
1. Name the two main labs and who was in charge of the projects.
2.​How many different labs were working on the project at that time? Name a few.
3. List a few of the problems they faced with the project.
4.​What date did the labs have 1/3 of the human genome sequenced?

Section 6: Genetic Variation
1. Whose genes were actually sequenced?
2. How different are any 2 humans?
3. Which kinds of animals are most different from each other – humans or chimpanzees?
4. Why are we as humans more closely related genetically than chimpanzees?
5. The human genome evolved from this continent __________ .
6​Explain why the difference between us and the banana genome are only 50% different.
7. ​Compare the human genome to the yeast genome.

Wrap-up study:
Easiest way to get to the website for this study: http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=gnd&ref=toc
At the new page titled Genes and Diseases, click on one of the 24 chromosomes shown at the top of the page
When the chromosome comes up, make note of the chromosome you choose.
​Note how many genes are located on the particular chromosome that you choose.
​Click on a disorder located on this chromosome and read about the particular disorder.
​Briefly give the characteristics of this genetic disorder.

If all else fails and the URL at the top of the Wrap-up study does not get you where you need to be, try the following:
1.​Select the web site http://www.ornl.gov/sci/techresources/Human_Genome/posters/chromosome/
2.​Click on Disorder Guide
3.​Scroll down to Gene and Diseases . Click on this hot link.
4.​On the page below the title Genes and Diseases click on the words “Click here”
5.​At the new page titled Genes and Diseases, click on one of the 24 chromosomes shown at the top of the page.
6. ​From here follow the directions for the activity listed in the Wrap-up study.
​